Project Finance Manager (Clinical Trial Proposals)

PSI CRO·São Paulo, SP, Brazil

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About the role

Hybrid Project Finance Manager role in São Paulo supporting clinical trial proposals and projects. Responsibilities include preparing and managing study budgets, sponsor contracts, change orders, payment schedules, accrual reports and invoices, plus timesheet and cost reconciliation. Requires a college or university degree, at least three years of CRO project budgeting and financial analysis experience, CEFR C1 English, advanced Excel, and strong analytical, communication and organizational skills.

Key requirements

• College or University degree, preferably in Finance/Economics
• At least 3 years of relevant experience
• Required skills: Project budgeting in a CRO, Financial analysis in a CRO, Clinical project budget development and management, Sponsor contract and change-order preparation, Payment schedule development, Accrual report preparation, Invoice request management, Project finance system setup and maintenance, Timesheet system management, Actual-versus-budget cost reconciliation, Advanced Microsoft Excel, Standard Microsoft Office applications, Analytical skills, Communication and negotiation, Organization and time management, Accurate and timely report production, Multitasking, Training others, English proficiency at CEFR C1 level
• Required language: English

Opportunity details

• Workplace: Hybrid
• Posted: Sep 24, 2026
• Original advert language: English

Full vacancy

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Employer’s role description

Job title: Project Finance Manager (Clinical Trial Proposals)

Location: São Paulo, SP, Brazil

Employment type: Full-time

Workplace type: Hybrid

Company Description

PSI is a leading Contract Research Organization (CRO) with 30 years of experience in the pharmaceutical industry. Originated in Switzerland, PSI is a privately owned, full-service CRO with a global reach, supporting clinical trials across multiple countries and continents. Our reputation for being highly selective about the projects we undertake highlights our commitment to delivering high-quality, timely services across a broad spectrum of therapeutic indications.

At PSI, we foster an environment where a diverse range of colleagues feel welcomed and valued. Our inclusive culture is a cornerstone of our success, enabling us to attract and retain top talent globally.

We are not just about conducting clinical trials; we are about building a community where every team member has the opportunity to thrive and contribute to groundbreaking advancements in the pharmaceutical industry.

Job Description

Please submit your CV in English

We are looking for experienced candidates to fill the Project Finance Manager position, and to be involved in clinical project budgeting, negotiating and analyzing budgets as well as providing support with proposals and contract management activities within the company.

Responsibilities:

Development of study budget (preparation of budgets for proposals and Change Order budgets for on-going projects)
Management of study budget throughout the clinical project duration (setup and maintenance of project finance information in PSI internal systems, preparation of accrual reports, request for invoices)
Development of Sponsor Contract (preparation of sponsor agreements and change orders, development of payment schedules)
Timesheet System Management (setup and maintenance of project-specific timesheets in PSI’s internal system, management of reconciliation of actual vs budget costs on a regular basis)

Qualifications

College or University degree, preferably in Finance/Economics
At least 3 years' experience in project budgeting and financial analysis in a CRO
Common European Framework of Reference for Language (CEFR) C1 level in English
Proficiency in standard MS Office applications, advanced use of MS Excel
Strong analytical skills
Strong communication/negotiation skills
Strong organizational and time management skills
Ability to communicate with all involved departments and sponsors
Ability to produce accurate and timely information/reports
Ability to work under pressure and to perform multi-task activities
Ability to train others

Additional Information

If you feel it is time to make your skills and knowledge visible within a growing company with true focus on its people, then PSI is the right choice for you.